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HIV/AIDS still largely a taboo subject in Hong Kong and much of East Asia

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The stigma over Aids is the biggest obstacle in diagnosing and treating patients in Asia, but Hong Kong is among a regional group that’s stepping up efforts to combat the disease

A child visits a Treat Asia network clinic in Kuala Lumpur. (photo: SCMP)

HIV/AIDS was presented in positive fashion in Hong Kong last week, thanks to celebrities such as Victoria Beckham, Gwyneth Paltrow and Michelle Yeoh, in town to attend a fundraising gala dinner by amfAR, the Foundation for Aids Research.

But on the whole, the disease is still a taboo subject in Hong Kong and the region. The stigma attached to it is still the biggest obstacle in diagnosing and treating patients, and preventing the disease from spreading.

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New edition: HIV, mental health & emotional wellbeing booklet
نسخه جدید: اچ آی وی، سلامت روان و جزوه سلامت احساس وعاطفه

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زندگی خوب با اچ آی وی

مراقبت از سلامتی خود را فقط در مورد آزمایش های پزشکی، مصرف داروهای ضد ویروسی، خوب غذا خوردن و ورزش نیست، اگر چه تمام این چیز ها مهم هستند. مشکلات عاطفی و مشکلات با سلامت روان می تواند هر کسی را تحت تاثیر قرار بدهد، اما زندگی با یک بیماری طولانی مدت مانند اچ آی وی، به این معناست که احتمال دارد شما بیشتر  به تجربه مشکلات روحی و روانی مواجه شوید.  این جزوه که به زبان انگلیسی نوشته شده، اطلاعاتی در مورد سلامت احساسی و سلامت روان برای افرادی که مبتلا به اچ آی وی هستند و با آن زندگی می کنند فراهم می کند. تجربیاتی در دسترس می باشد که شما می توانید از سلامت عاطفی خود هنگام مشکلاتتان در مسیر زندگی و بیماری مواظبت کنید. بطور نمونه در درمان افسردگی، ترس و نگرانیها و بسیاری دیگر از مشکلات روحی و روانی موثر باشد. همچنین برای پیدا کردن پشتیبانی، چه از دوستان و خانواده، و یا سازمان های حمایت از جامعه می تواند نقش بزرگی برای شما ایجاد کند. این جزوه به روش پی دی اف و به زبان انگلیسی می باشد. شما می توانید روی لینک پایین کلیک کنید، آنرا باز کرده و بخوانید.

جزوه – روی همین لینک کلیک کنید:  HIV, mental health & emotional wellbeing booklet

برگردان: کیومرث سراج الهی

Living well with HIV

Looking after your health is not just about medical tests, taking antiretroviral treatment, eating well and exercising, although all of these things are important. Emotional difficulties and problems with mental health can affect anybody, but living with a long-term illness like HIV can mean that you are more likely to experience mental health problems. This booklet provides information on emotional wellbeing and mental health for people living with HIV.

There are things you can do to look after your emotional health, and help available if you do experience problems. Treatment for depression, anxiety and many other mental health problems can be very effective, and finding support, whether from friends and family, or community support organisations can make a big difference.

Read it online: HIV, mental health & emotional wellbeing booklet

Source: nam aidsmap

Co-trimoxazole prophylaxis and people with HIV

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کوتریموکسازول برای پیشگیری از بیماریهای فرصت طلب برای مبتلایان به اچ آی وی

داروی کوتریموکسازول برای پیشگیری از مرگ و میر و عوارض جانبی ویروس اچ آی وی از جمله عفونت های شدید باکتریایی، سل، ذات الریه، اسهال، مالاریا، و یا درمان محدود عوارض جانبی. پیشگیری از مرگ و میر نوزادان به دلیل بیماری مالاریا یا درمان پیشگیرانه متناوب برای مالاریا در زنان باردار استفاده می شود.
کوتریموکسازول در کشورهای کم درآمد و نیز پر در آمد می بایست همراه با داروهای آرت یا آنتی رترو ویرال برای درمان مبتلایان به اچ آی وی بویژه کسا نی که سلولهای کمکی بدن آنها زیر 350 میکرولیتر یا پایین تر می باشد بکار برده می شود. زیرا سیستم ایمنی بدن این مبتلایان ضعیف بوده و آنان آمادگی هر گونه بیماری جانبی ناشی از عفونت اچ آی وی را دارا هستند. 
زنان باردار مبتلا به اچ آی وی در آفریقا باید برای جلوگیری از عوارض بیماری مالاریا در نوزادان از این دارو نیز استفاده کنند. کوتریموکسازول روزانه یک عدد با دوز 480 میلی گرم  یا 960 میلی گرم به بیماران تجویز می شود.

برگردان از مجله لانست: کیومرث سراج الهی

Introduction

Co-trimoxazole prophylaxis is used to reduce morbidity and mortality in people with HIV. We systematically reviewed three topics related to co-trimoxazole prophylaxis to update WHO guidelines: initiation, discontinuation, and dose.

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Antiretroviral Therapy in 2015

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تعدادی از داروهای ضد ویروس اچ آی وی سال 2015 میلادی، داروهایی هستند که در گذشته تولید شده اند و هنوز برای درمان مبتلایان به ویروس اچ آی وی و بیماران به ایدز بکار برده می شوند. اما با این تفاوت که داروهای از نوع جدید با کیفیت بهتر و با عوارض جانبی کمتری برای بدن برخوردار می باشند. داروهای جدید، ترکیبی (از چند دارو ساخته شده) نیز می باشند. به همین دلیل بیماران روزانه تعداد کمتری دارو مصرف خواهند کرد، که این خود گام بسیار خوبی برای آسانتر ساختن درمان مبتلایان و بیماران می باشد. اینک این داروها در بازار در دسترس بیماران قرار دارند.

برگردان: کیومرث سراج الهی

One doctor’s perspective On the state of HIV TREATMENT

By Joel Gallant, MD, MPH

Antiretroviral therapy (ART) options continue to expand and improve, making antiretroviral therapy (ART) easier, better tolerated, and more convenient. In this article, I’ll discuss my own opinions on options for initial therapy, and what’s in the pipeline.

Foto: Dr. Katharina Thiele, MHBA / HIV&more

Foto: Dr. Katharina Thiele, MHBA / HIV&more

Initial Therapy

There’s a wealth of potential options for first-line therapy, but only a few combinations that we’re now starting with on a regular basis. Integrase inhibitors are hot these days, because in trial after trial, they’re either as good or better than older regimens, with clear tolerability advantages. Speaking for myself, there are just a handful of “go-to” regimens for patients starting ART without baseline resistance, listed here in no particular order.

  • Stribild
  • Triumeq
  • Tivicay plus Truvada
  • Boosted Prezista plus either Truvada or Epzicom

Of course, I have patients on many other first-line regimens. There’s no reason to switch therapy in someone doing well on Atripla, Complera, Viramune, or Isentress, for example. But I generally stick with one of the choices mentioned above if I’m starting ART for the first time. Here’s why.

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Elizabeth Taylor’s Grandkids are AIDS Activists, Too

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Elizabeth Taylor with her granddaughter Naomi Wilding at a private dinner held in Taylor's honor on March 18, 2003 at the Frederick R. Weisman Art Foundation in Los Angeles, California. Taylor received the first-ever Diamond Icon Award for her courage and leadership in the fight against AIDS. © Dan Steinberg/Getty Images

Elizabeth Taylor with her granddaughter Naomi Wilding at a private dinner held in Taylor’s honor on March 18, 2003 at the Frederick R. Weisman Art Foundation in Los Angeles, California. Taylor received the first-ever Diamond Icon Award for her courage and leadership in the fight against AIDS. © Dan Steinberg/Getty Images

The Hollywood legend founded AIDS organizations, inspired generations of people with HIV, and left behind a family tree of people who continue to work on our causes.

The Hollywood starlet turned film legend left another legacy of equal importance: She founded or benefited a number of AIDS organizations, inspired generations of people with HIV, moved policy and politicians, and left behind a family tree of people who continue to work on HIV and AIDS causes. Here’s what she begot.

Organizations Taylor Founded

National AIDS Research Foundation: In Los Angeles in 1985, Taylor and Dr. Michael Gottlieb cofounded the National AIDS Research Foundation to research, find a cure and help people living with AIDS. At the same, Dr. Mathilde Krim established the AIDS Medical Research Foundation. These two merged to become…amfAR, cofounded by Krim and Gottlieb with Taylor as its international founding chairperson. With the success of amfAR and people with HIV beginning to live longer, Taylor established the Elizabeth Taylor AIDS Foundation in 1991 to focus specifically on funding organizations that cared for individuals with HIV or AIDS. Taylor sold her wedding photos to People for $1 million and used the money in its entirety to open the doors of ETAF. To date, more than 650 organizations in 33 countries have been helped through ETAF’s funding efforts.

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Stopping HIV with an artificial protein

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An aerial view of HIV’s surface proteins (blobs) shows how eCD4-Ig can bind to the virus and “neutralize” it. (adapted from Michael Farzan et al., Nature, 2015)

An aerial view of HIV’s surface proteins (blobs) shows how eCD4-Ig can bind to the virus and “neutralize” it. (adapted from Michael Farzan et al., Nature, 2015)

For 30 years, researchers have struggled to determine which immune responses best foil HIV, information that has guided the design of AIDS vaccines and other prevention approaches. Now, a research team has shown that a lab-made molecule that mimics an antibody from our immune system may have more protective power than anything the body produces, keeping four monkeys free of HIV infection despite injection of large doses of the virus.

Intensive hunts are under way for natural HIV antibodies that can stop—or “neutralize”—the many variants of the constantly mutating AIDS virus. Researchers have recently found several dozen broadly neutralizing antibodies (bNAbs) that are highly potent and work at low doses. But viral immunologist Michael Farzan of the Scripps Research Institute in Jupiter, Florida, and 33 co-workers have recently taken a different strategy, building a novel molecule based on our knowledge of how HIV infects cells. HIV infects white blood cells by sequentially attaching to two receptors on their surfaces. First, HIV’s own surface protein, gp120, docks on the cell’s CD4 receptor. This attachment twists gp120 such that it exposes a region on the virus that can attach to the second cellular receptor, CCR5. The new construct combines a piece of CD4 with a smidgen of CCR5 and attaches both receptors to a piece of an antibody. In essence, the AIDS virus locks onto the construct, dubbed eCD4-Ig, as though it were attaching to a cell and thus is neutralized.

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Why Canada’s African, Caribbean and Black Communities Are Most Affected by HIV and AIDS

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ACBCHAAD_Poster_smallLast year Joseph walked into a downtown emergency room with a persistent cough and trouble breathing. After a long wait he was examined by a doctor and was immediately admitted. He had a serious case of pneumonia that was getting worse by the day. After some testing Joseph was informed that he was living with HIV and that his body’s immune system had almost lost its ability to fight off infections. Joseph had AIDS and he was totally unaware of it.

For those of us working in the Canadian HIV field, this is an all too common scenario. The reality is that out of all Canadians living with HIV, more than one in four don’t know they are living with it. And for those of us working with African, Caribbean and Black communities in Canada, it doesn’t surprise us to learn that Joseph is a Black man. People from African, Caribbean and Black communities in Canada are disproportionately affected by HIV and AIDS. They represent approximately 15% (one in seven) of people living with HIV in Canada while representing only 2.5% of the population. The national numbers also show that if you are Black in Canada, you are about 9 times more likely to become infected with HIV than other Canadians.

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Delhi: Transgender voters fight hard, demand they be treated equally

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هلی نو: رای دهندگان فراجنسیتی سخت مبارز، تقاضای آنها رفتار به طور مساوی با آنان, به مانند سایر مردم جامعه است.

من دیگری نیستم. من یک درخت نیستم، من یک اتوبوس نیستم، من یک قطار نیستم، یک سگ یا گربه. من یک فرد هستم. من هویتم را می خواهم. من یک ترانس هستم، یک دختر.  گفت: نوری

برگردان: کیومرث سراج الهی

Indian eunuchs show their voter identity cards showing their gender as “other”. This is the first election that the country’s transgender/eunuch community will be voting after India’s Supreme Court has recognised transgender people as a third gender. © AFP / Indranil Mukherjee

New Delhi: It is a forgotten community and an almost forgotten vote bank, but nearly 1 lakh transgenders will be voting in Delhi on December 4. They have just one basic demand, that is to be treated equally.

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Canadians already on PrEP while drug sits in regulatory limbo

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آیا شما اچ آی وی منفی هستید و مایلید که همین گونه وضعیت تندرستی شما باقی بماند؟  روزانه یک عدد قرص تراوادا راه حل بسیار مناسبی برای پیشگیری از ابتلا به به ویروس عفونی اچ آی وی است.
داروی تراواد برای پیشگیری از ابتلا به عفونت اچ آی وی و همچنین درمان برای مبتلایان به ویروس اچ آی وی و بیماران ایدز.
برگردان: کیومرث سراج الهی

You’re HIV-negative. You’d like to stay that way. Is a daily dose of pre-exposure prophylaxis the solution?

photo: Daily Xtra

photo: Daily Xtra

It works like the birth control pill. It’s a once-a-day tablet. It can have side effects, but for most, it’s relatively safe. Like birth control, it works only if you actually take it every day. And it doesn’t prevent sexually transmitted infections like chlamydia and gonorrhea.

The difference is this pill doesn’t prevent pregnancy. It prevents HIV.

The drug is Truvada, which is a common first-line treatment for people who are HIV-positive. But doctors are beginning to prescribe it to people who are HIV-negative as a way of keeping them negative, part of a strategy called pre-exposure prophylaxis, or PrEP for short.

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Ways of coping with AIDS: opinion of mothers with HIV children*

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The Mentor Mother program trains women to provide health information and conduct home visits to pregnant women and to help the mothers raise healthier children. )Credit: Image courtesy of University of California, Los Angeles (UCLA), Health Sciences)

The Mentor Mother program trains women to provide health information and conduct home visits to pregnant women and to help the mothers raise healthier children. Credit: Image courtesy of University of California, Los Angeles (UCLA), Health Sciences

ABSTRACT

The research aims at identifying strategies of coping with AIDS used by mothers of HIV positive children to live better with their children’s disease. The method used was a descriptive qualitative study. Thirty-three structured interviews were conducted with HIV positive women voluntaries and registered as users in the clinic of the public hospital of reference for the treatment of AIDS in Natal/RN. For data analysis, the method used was thematic content analysis. From the analysis, prevalent categories regarding forms of facing AIDS came up, they were: overprotection and fear; donation; hope; religious belief; underestimation of HIV; hiding the diagnosis; and resignation. This study shows that despite AIDS limitations and barriers, relatives develop strategies that make it possible to face every day problems and live better with it.

Descriptors: HIV; acquired immunodeficiency syndrome; HIV seropositivity; mothers; coping behavior

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